Micronutrients in Life Expectancy and Ageing (MILEAGE)

Ageing is a process in which damage to cells from oxidising conditions cannot be fully repaired, and the cumulative effect is a gradual deterioration of cellular function. Some micronutrients protect against oxidative stress but due to ageing, less micronutrients may be absorbed from food or retained by the body and a deficiency within cells can accelerate the ageing process.

The objective of this project is to determine the mechanisms controlling zinc and copper absorption and excretion that are sensitive to oxidative damage and which are potential targets for therapeutic approaches to increase control of metal homeostasis and therefore life expectancy.

The project is a Marie Skłodowska-Curie action under the Research and Innovation Staff Exchange (RISE) scheme of the European Union. The partners are from France, UK, Ukraine, Jamaica and Chile.